Open source focus
Open Source Alternatives to ArcaScience
60 open source AI-Driven Drug Discovery options similar to ArcaScience, ranked by named competitors first, sector overlap, and our 0-100 AI-readiness score. Each profile notes license and self-hosting where we have it.
Carta Healthcare54HealthTechSan Francisco, United StatesOpen source
Axonmedical4HealthTechOpen source
OmniarxAI-Driven Drug DiscoveryOpen source
Converge Bio56Life SciencesSan Francisco, United States$5.5MOpen source · Self-hostable
Pluromica40AI InfrastructureSan Francisco, United StatesOpen source
Biolinked21AI-Driven Protein DesignTel Aviv, IsraelOpen source
Oncometra17AI-Driven Drug DiscoveryOpen source
Amadeusbio6BiotechOpen source
RegenxcelBiotechOpen source
AI Health FundArtificial IntelligenceNew York, United StatesOpen source
PeptideanswersAI Drug DiscoveryOpen source
H2O.ai64Foundation ModelMountain View, United States$228.1MOpen source · Self-hostable
Weights & Biases (W&B)63MLOpsSan Francisco, United States$521.0MOpen source
Warp59AI Tools & AppsSan Francisco, United States$60.0MOpen source
Traceloop55LLMOpsTel Aviv, Israel$6.1MOpen source
Neuronics54AI Drug DiscoverySan Francisco, United StatesOpen source
Feast AI54MLOpsSan Francisco, United StatesOpen source · Self-hostable
MosaicML (now Databricks)54Foundation ModelSan Francisco, United States$21.7MOpen source
LlamaIndex Inc.53Foundation ModelSan Francisco, United StatesOpen source · Self-hostable
Superlinked53Artificial IntelligenceTel Aviv, Israel$9.5MOpen source
Visual Layer50DatabaseTel Aviv, Israel$7.0MOpen source · Self-hostable
nao Labs50Agentic AISan Francisco, United StatesOpen source
Insight Axis46HealthcareBoston, United StatesOpen source
JarvisLabs.ai43MLOpsSan Francisco, United StatesOpen source
ScaleKit42MLOpsSan Francisco, United States$5.5MOpen source
Neptune41MLOpsNew York, United States$11.0MOpen source
OuterBounds Technologies, Inc.41MLOpsSan Francisco, United StatesOpen source
- SOSource32AI InfrastructureSan Francisco, United States$24.0M
Open source · Self-hostable
DenovAI Biotech29Life SciencesRehovot, IsraelOpen source
Bitrawr25AI Tools & AppsTel Aviv, IsraelOpen source
Quanteta Data Lab21Data PlatformOpen source
Fibrotherapeutics18HealthTechOpen source
Trialiq17HealthTechTel Aviv, IsraelOpen source
- Mhccm14HealthTech
Open source
Search House AI14AI Search EngineTel Aviv, IsraelOpen source
LlamaAi (DefiLlama)10FintechOpen source
Google Cloud AI8AI Foundation & ComputeMountain View, United StatesOpen source
Google Cloud Vertex AI8MLOpsMountain View, United StatesOpen source
HockitAI Search EngineTel Aviv, IsraelOpen source
EazycareHealthTechOpen source
VektorsearchpartnersAI Search EngineTel Aviv, IsraelOpen source
ShopcodexE-commerceTel Aviv, IsraelOpen source
FxframeworkFintechLondon, United KingdomOpen source
AioptogeneticsNeurotech & HCITel Aviv, IsraelOpen source
AllbioBiotechOpen source
DrivecorpsAI InfrastructureOpen source
DupixentHealthTechOpen source
RolledalloysAI InfrastructureOpen source
OpenAI84Artificial IntelligenceSan Francisco, United States$493.9BOpen source
- XAxAI78Frontier AI LabPalo Alto, United States$90.0B
Open source
Together AI76AI InfrastructureSan Francisco, United States$906.0MOpen source · Self-hostable
NemoClaw75Artificial IntelligenceOpen source · Self-hostable
Manus AI75Agentic AISingapore, Singapore$150.0MOpen source
Thinking Machines Lab74Frontier AI LabSan Francisco, United States$3.4BOpen source
Runway AI72Generative AINew York, United States$666.5MOpen source
Perplexity AI71Search EngineSan Francisco, United States$591.4MOpen source
runway gen 571Generative AINew York City, United States$859.5MOpen source
OpenRouter70InfrastructureSan Francisco, United States$153.5MOpen source
DeepSeek AI70AI InfrastructureBeijing, ChinaOpen source
Pinecone69AI InfrastructureSan Francisco, United States$138.0MOpen source
| Company | Sector | License | HQ | Funding | Score |
|---|---|---|---|---|---|
| Carta Healthcare | HealthTech | Open source | San Francisco, United States | — | 54 |
| Axonmedical | HealthTech | Open source | — | — | 4 |
| Omniarx | AI-Driven Drug Discovery | Open source | — | — | — |
| Converge Bio | Life Sciences | Open source · Self-hostable | San Francisco, United States | $5.5M | 56 |
| Pluromica | AI Infrastructure | Open source | San Francisco, United States | — | 40 |
| Biolinked | AI-Driven Protein Design | Open source | Tel Aviv, Israel | — | 21 |
| Oncometra | AI-Driven Drug Discovery | Open source | — | — | 17 |
| Amadeusbio | Biotech | Open source | — | — | 6 |
| Regenxcel | Biotech | Open source | — | — | — |
| AI Health Fund | Artificial Intelligence | Open source | New York, United States | — | — |
| Peptideanswers | AI Drug Discovery | Open source | — | — | — |
| H2O.ai | Foundation Model | Open source · Self-hostable | Mountain View, United States | $228.1M | 64 |
| Weights & Biases (W&B) | MLOps | Open source | San Francisco, United States | $521.0M | 63 |
| Warp | AI Tools & Apps | Open source | San Francisco, United States | $60.0M | 59 |
| Traceloop | LLMOps | Open source | Tel Aviv, Israel | $6.1M | 55 |
| Neuronics | AI Drug Discovery | Open source | San Francisco, United States | — | 54 |
| Feast AI | MLOps | Open source · Self-hostable | San Francisco, United States | — | 54 |
| MosaicML (now Databricks) | Foundation Model | Open source | San Francisco, United States | $21.7M | 54 |
| LlamaIndex Inc. | Foundation Model | Open source · Self-hostable | San Francisco, United States | — | 53 |
| Superlinked | Artificial Intelligence | Open source | Tel Aviv, Israel | $9.5M | 53 |
| Visual Layer | Database | Open source · Self-hostable | Tel Aviv, Israel | $7.0M | 50 |
| nao Labs | Agentic AI | Open source | San Francisco, United States | — | 50 |
| Insight Axis | Healthcare | Open source | Boston, United States | — | 46 |
| JarvisLabs.ai | MLOps | Open source | San Francisco, United States | — | 43 |
| ScaleKit | MLOps | Open source | San Francisco, United States | $5.5M | 42 |
| Neptune | MLOps | Open source | New York, United States | $11.0M | 41 |
| OuterBounds Technologies, Inc. | MLOps | Open source | San Francisco, United States | — | 41 |
| SOSource | AI Infrastructure | Open source · Self-hostable | San Francisco, United States | $24.0M | 32 |
| DenovAI Biotech | Life Sciences | Open source | Rehovot, Israel | — | 29 |
| Bitrawr | AI Tools & Apps | Open source | Tel Aviv, Israel | — | 25 |
| Quanteta Data Lab | Data Platform | Open source | — | — | 21 |
| Fibrotherapeutics | HealthTech | Open source | — | — | 18 |
| Trialiq | HealthTech | Open source | Tel Aviv, Israel | — | 17 |
| HealthTech | Open source | — | — | 14 | |
| Search House AI | AI Search Engine | Open source | Tel Aviv, Israel | — | 14 |
| LlamaAi (DefiLlama) | Fintech | Open source | — | — | 10 |
| Google Cloud AI | AI Foundation & Compute | Open source | Mountain View, United States | — | 8 |
| Google Cloud Vertex AI | MLOps | Open source | Mountain View, United States | — | 8 |
| Hockit | AI Search Engine | Open source | Tel Aviv, Israel | — | — |
| Eazycare | HealthTech | Open source | — | — | — |
| Vektorsearchpartners | AI Search Engine | Open source | Tel Aviv, Israel | — | — |
| Shopcodex | E-commerce | Open source | Tel Aviv, Israel | — | — |
| Fxframework | Fintech | Open source | London, United Kingdom | — | — |
| Aioptogenetics | Neurotech & HCI | Open source | Tel Aviv, Israel | — | — |
| Allbio | Biotech | Open source | — | — | — |
| Drivecorps | AI Infrastructure | Open source | — | — | — |
| Dupixent | HealthTech | Open source | — | — | — |
| Rolledalloys | AI Infrastructure | Open source | — | — | — |
| OpenAI | Artificial Intelligence | Open source | San Francisco, United States | $493.9B | 84 |
| XAxAI | Frontier AI Lab | Open source | Palo Alto, United States | $90.0B | 78 |
| Together AI | AI Infrastructure | Open source · Self-hostable | San Francisco, United States | $906.0M | 76 |
| NemoClaw | Artificial Intelligence | Open source · Self-hostable | — | — | 75 |
| Manus AI | Agentic AI | Open source | Singapore, Singapore | $150.0M | 75 |
| Thinking Machines Lab | Frontier AI Lab | Open source | San Francisco, United States | $3.4B | 74 |
| Runway AI | Generative AI | Open source | New York, United States | $666.5M | 72 |
| Perplexity AI | Search Engine | Open source | San Francisco, United States | $591.4M | 71 |
| runway gen 5 | Generative AI | Open source | New York City, United States | $859.5M | 71 |
| OpenRouter | Infrastructure | Open source | San Francisco, United States | $153.5M | 70 |
| DeepSeek AI | AI Infrastructure | Open source | Beijing, China | — | 70 |
| Pinecone | AI Infrastructure | Open source | San Francisco, United States | $138.0M | 69 |