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This curated list features startups developing unified APIs for AI agents. These companies provide foundational infrastructure that enables AI agents to interact with various tools and services seamlessly via a unified API interface. The directory is designed for founders building AI agent platforms, investors seeking to understand the AI infrastructure landscape, and AI researchers exploring agent interoperability. Discover companies like Integuru and Orthogonal that are simplifying AI agent integration.
Startups

#1
Oxide AI
Oxide AI offers a Custom AI Agent API to build smart and robust AI agents with powerful reasoning capabilities for dynamic real-world environments.

#2
AgentMail
API-first email infrastructure for AI agents, offering dedicated inboxes and overcoming traditional provider limitations.

#3
Truffle AI (YC W25)
Truffle AI provides an AI agent development platform that enables businesses to build, customize, and deploy AI agents to automate and unify workflows in minutes.

#4
Parsewise
Parsewise provides multi-document processing and analysis that can be embedded in products, offering an API to replace complex processing pipelines for AI agents.

#5
Inconvo
Inconvo is an open-source platform for building data agents on production data with safe queries, permissions, and structured outputs.
#6
Opensteer
Opensteer creates specialized AI agents in cloud computers that can integrate with anything, offering customizable browser access, tools, instructions, and guardrails.

#7
Tesora
Tesora builds agents for actuaries at P&C carriers, reinsurers, and MGAs, providing an agentic workbench that ingests data and builds, audits, and deploys raters and pricing analyses.

#8
Composio
AI skill layer enabling agents to reliably interact with over 3000 real-world tools and APIs.

#9
Nango
Nango is an open-source platform for product integrations that provides a unified API for connecting to over 500 services and supports tool-calling for AI agents.

#10
Arcade AI, Inc
AI-powered platform automating customer support and sales processes for enhanced efficiency and satisfaction.
#11
Coverflex
Digital employee benefits platform for modern companies.

#12
Apideck
Apideck is a Unified API platform that simplifies API integrations and is integrating LLMs into its APIs to enable real-time data retrieval for AI agents.
#13
Jentic
AI-powered enterprise software for supply chain and operations.

#14
Integuru
Generates fast, reliable APIs for any platform using direct HTTP requests.

#15
Orthogonal
Agentic Payments for APIs
List Stats