Open Source Alternatives to Dotmatics
60 open source Biotech options similar to Dotmatics, ranked by named competitors first, sector overlap, and our 0-100 AI-readiness score. Each profile notes license and self-hosting where we have it.
Aemetis15Climate TechCupertino, United StatesAemetis is a renewable fuels and biochemicals company focused on low-carbon solutions like RNG and SAF.
Open source · Self-hostable
Enzymit56HealthcareTel Aviv, Israel$10.0MDesigns and creates novel enzymes for sustainable and cost-effective bioproduction.
Open source
SpotitEarly55HealthcareTel Aviv, Israel$6.2MScent-based multi-cancer early detection screening test using AI and bio-detectors.
Open source
Ultragenyx55BiotechNovato, United States$100.0MBiopharmaceutical company developing novel therapies for rare and ultra-rare genetic diseases.
Open source
Arrakis Bio51Life SciencesCambridge, United StatesArrakis Bio is developing novel therapeutics for cancer and other diseases using a proprietary gene editing platform.
Open source
Sequentify49HealthcareSan Francisco, United States$7.0MMaking targeted DNA sequencing as common, fast, and affordable as a blood test.
Open source
Seqera Labs46BiotechBarcelona, SpainCloud-native platform for scalable and reproducible bioinformatics workflows.
Open source
VI Therapeutics42Life SciencesCambridge, United StatesVI Therapeutics is developing novel therapies for rare genetic diseases.
Open source
Regenxcel7BiotechRegenxcel AI transforms cell and gene manufacturing with cutting-edge AI technology for enhanced efficiency and precision.
Open source
WekaIO70ComputingCampbell, United States$565.0MWEKA is a data platform for AI and HPC workloads, delivering extreme performance for GPU clusters, genomics pipelines, and data-intensive applications.
Open source
BioSymetrics63BiotechBoston, United States$6.6MPhenomics-driven AI company translating disease biology into precision medicine discoveries.
Open source
Converge Bio56Life SciencesSan Francisco, United States$5.5MComputational platform using LLMs trained on biological and chemical data for drug discovery.
Open source · Self-hostable
ZipBio55Life SciencesCambridge, United States$4.0MCompressing biology to develop the next generation of therapies.
Open source
PFx Biotech51BiotechCambridge, United States$5.2MPFx Biotech is developing a novel platform for the discovery and development of protein-based therapeutics.
Open source
Evogene50Computational BiologyRehovot, Israel$7.9MComputational biology company revolutionizing life sciences product discovery and development using predictive biology.
Open source
Curoverse48GenomicsBoston, United States$3.2MProvides genomic and biomedical computing solutions for managing and analyzing large datasets.
Open source · Self-hostable
MNDL Bio47Life SciencesSan Francisco, United States$2.0MSynthetic biology startup optimizing gene expression for food and biotech applications.
Open source
iSpecimen .46BiotechPlainsboro, United States$1.0MGlobal marketplace connecting researchers with human biospecimens for life science research.
Open source
PhenoTA45Life SciencesBoston, United StatesLeveraging AI and novel technology to extract deep health insights from routine blood tests.
Open source
Anamnesis Bio42Biotechתל אביב - יפו, IsraelDeveloping novel therapeutics for neurodegenerative diseases using advanced biological insights.
Open source
BoobyBiome41HealthTechLondon, United Kingdom$4.2MDeveloping a microbiome-based diagnostic for early breast cancer detection.
Open source
Alvox Bio31Life SciencesCambridge, United StatesAlvox Bio is a life sciences startup developing novel therapeutic antibodies.
Open source
DenovAI Biotech29Life SciencesRehovot, IsraelDenovAI Biotech leverages AI for de novo protein design, focusing on novel therapeutics and diagnostics.
Open source
SensifAI Health29HealthcareTel Aviv, IsraelAI-powered platform for personalized health insights and early disease detection.
Open source
Biolinked23AI-Driven Protein DesignAI-powered platform for scientific research, connecting researchers and accelerating discovery.
Open source
Fibrotherapeutics20HealthTechDiscover innovative AI therapeutics at fibrotherapeutics.ai, enhancing patient care and advancing health technology.
Open source
Allbio8BiotechExplore cutting-edge bio technology solutions with AI, launching soon.
Open source
Omniarx7AI-Driven Drug DiscoveryAI-powered platform for accelerating drug discovery and development.
Open source
Amadeusbio6BiotechAmadeusBio.ai provides an agentic bioinformatics toolkit as a Claude Code plugin for natural language analysis and data retrieval.
Open source
InstaDeep71Decision-Making AITunis, Tunisia$177.0MInstaDeep is a global AI leader specializing in decision-making AI systems for enterprises, with roots in Africa and offices worldwide.
Open source
Pinecone69AI InfrastructureSan Francisco, United States$138.0MManaged vector database for building scalable, reliable, and accurate AI applications and search.
Open source
Ultima Genomics68Life SciencesRehovot, Israel$15.0MUnleashing the power of genomics at scale for biological advances and human health.
Open source
Starburst67AIBoston, United States$414.0MData platform for apps and AI, unifying distributed data for analytics and AI innovation.
Open source · Self-hostable
YugabyteDB67DatabaseSunnyvale, United States$266.0MDistributed SQL database for cloud-native applications, offering high availability and horizontal scalability.
Open source · Self-hostable
PostgreSQL66DatabaseSanta Barbara, USAA powerful, open-source object-relational database system known for reliability and extensibility.
Open source · Self-hostable
M-Files Content Collaboration63Enterprise SoftwarePlano, United States$201.0MIntelligent content management and automation platform for enterprise information.
Open source
Elicit62Artificial IntelligenceOakland, United States$31.0MAI-powered research assistant for scientific literature review and data extraction.
Open source
Workiva62Enterprise SoftwareAmes, United StatesAI-powered platform unifying data and processes for finance, accounting, sustainability, risk, and audit teams.
Open source
Akeneo62Product Information ManagementNantes, France$181.5MAkeneo provides a Product Information Management (PIM) and Product Experience Management (PXM) platform for brands and retailers.
Open source
Nasuni61SaaSBoston, United States$219.0MA hybrid cloud file data platform providing unified storage, protection, and management for enterprises.
Open source
InsideTracker61HealthTechBoston, United States$45.0MPersonalized health and performance insights based on blood biomarkers and DNA.
Open source
MariaDB61DatabaseRedwood City, United States$131.0MA cloud database company providing a unified platform for transactional, analytical, and AI workloads.
Open source · Self-hostable
Absci60BiotechVancouver, United States$100.5MAI-powered drug discovery and development platform for biologics.
Open source
Warp59AI Tools & AppsSan Francisco, United States$60.0MAI-powered platform for scientific research and discovery, accelerating hypothesis generation and experimentation.
Open source
GridGain Systems57Data ManagementFoster City, United States$15.0MIn-memory computing pioneer providing a unified real-time data platform for accelerated data processing.
Open source
Scala Biodesign56Life SciencesTel Aviv, Israel$21.5MDesigns proteins with superior properties using computational analysis, evolutionary insights, and AI.
Open source
FalkorDB55EnterpriseTel Aviv, Israel$3.0MQueryable property graph database using sparse matrices and linear algebra for graph queries.
Open source
ProteinQure54BiotechCambridge, United States$15.6MBiotech company using AI and computational platforms to design novel peptide therapeutics.
Open source
MemVerge54MemorySan Jose, United States$43.5MPioneering Big Memory Computing for cloud-native big data applications.
Open source
Dren Bio52BiotechSan Carlos, United States$156.0MBiopharmaceutical company developing antibody therapeutics for cancer and autoimmune diseases.
Open source
DBeaver52Database ManagementPrague, Czech Republic$6.0MA universal database management tool for developers and database administrators, supporting a wide range of databases.
Open source · Self-hostable
SOMAREALITY49Artificial IntelligenceVienna, Austria$3.0MReal-time cognitive insights through eye tracking.
Open source
Cardio Renal49HealthTechParis, France$13.7MFrench digital therapeutics company developing a non-invasive potassium monitoring device for CKD patients.
Open source
Tissue Dynamics47BiotechSan Diego, United StatesAI-powered platform for real-time organ physiology to accelerate human-relevant drug discovery.
Open source
Noobaa41EnterpriseSan Francisco, United States$5.0MNooBaa provides an open-source, S3-compatible object storage platform for managing data across private and public clouds.
Open source · Self-hostable
Symbiosis C.M.41HealthcareBoston, United States$10.0MMedical device company addressing anatomical variability in valvular heart disease.
Open source
Couchbase41DatabaseSan Jose, United States$39.0MA leading cloud-native distributed SQL database for modern applications.
Open source
Responsive40EnterpriseSan Francisco, United StatesPlatform for developers building stateful reactive applications on the modern cloud with object store native databases.
Open source · Self-hostable
Portworx40CloudTech & DevOpsSanta Clara, United States$35.5MCloud-native data services platform for Kubernetes, acquired by Pure Storage.
Open source
Countly40AnalyticsLondon, United Kingdom$1.1MProduct analytics and customer engagement platform built on an open-source, self-hosted foundation.
Open source · Self-hostable