Houdini Bio is a DeepTech BioTech company providing critical enabling infrastructure for next-generation genetic medicines. Their platform combines machine learning with a mechanistic understanding of cellular silencing pathways to re-engineer therapeutic DNA. This approach aims to maximize transgene expression, durability, and scalability by making therapeutic DNA invisible to cellular defenses like the Human Silencing Hub (HUSH) complex, thereby improving the effectiveness and safety of genetic therapies.