Open Source Alternatives to Polymodels Hub
60 open source 3D Modeling options similar to Polymodels Hub, ranked by named competitors first, sector overlap, and our 0-100 AI-readiness score. Each profile notes license and self-hosting where we have it.
Blender303D ModelingAmsterdam, NetherlandsFree and open-source 3D creation suite for animation, modeling, rendering, and more.
Open source · Self-hostable
CGTrader463D PrintingVilnius, LithuaniaA global marketplace for 3D models, offering a vast library for designers and developers.
Open source
Seqera Labs46BiotechBarcelona, SpainCloud-native platform for scalable and reproducible bioinformatics workflows.
Open source
Pluromica34AI InfrastructureOpen source
Regenxcel7BiotechRegenxcel AI transforms cell and gene manufacturing with cutting-edge AI technology for enhanced efficiency and precision.
Open source
BioSymetrics63BiotechBoston, United States$6.6MPhenomics-driven AI company translating disease biology into precision medicine discoveries.
Open source
Elicit62Artificial IntelligenceOakland, United States$31.0MAI-powered research assistant for scientific literature review and data extraction.
Open source
Converge Bio56Life SciencesSan Francisco, United States$5.5MComputational platform using LLMs trained on biological and chemical data for drug discovery.
Open source · Self-hostable
Ultragenyx55BiotechNovato, United States$100.0MBiopharmaceutical company developing novel therapies for rare and ultra-rare genetic diseases.
Open source
SpotitEarly53HealthcareTel Aviv, Israel$6.2MScent-based multi-cancer early detection screening test using AI and bio-detectors.
Open source
Arrakis Bio48Life SciencesCambridge, United StatesArrakis Bio is developing novel therapeutics for cancer and other diseases using a proprietary gene editing platform.
Open source
Sequentify48HealthcareSan Francisco, United States$7.0MMaking targeted DNA sequencing as common, fast, and affordable as a blood test.
Open source
Tissue Dynamics47BiotechSan Diego, United StatesAI-powered platform for real-time organ physiology to accelerate human-relevant drug discovery.
Open source
iSpecimen .46BiotechPlainsboro, United States$1.0MGlobal marketplace connecting researchers with human biospecimens for life science research.
Open source
Anamnesis Bio42Biotechתל אביב - יפו, IsraelDeveloping novel therapeutics for neurodegenerative diseases using advanced biological insights.
Open source
VI Therapeutics42Life SciencesCambridge, United StatesVI Therapeutics is developing novel therapies for rare genetic diseases.
Open source
CaleeTech34HealthcareTel Aviv, IsraelBiotech startup developing novel oral formulations for obesity and diabetes.
Open source
DenovAI Biotech27Life SciencesRehovot, IsraelDenovAI Biotech leverages AI for de novo protein design, focusing on novel therapeutics and diagnostics.
Open source
Bsense Bio Therapeutics24Life SciencesDeveloping small molecules to treat sensory hyperexcitability disorders like pain and tinnitus.
Open source
Biolinked23AI-Driven Protein DesignOpen source
Oncometra20AI-Driven Drug DiscoveryOncometra is developing an AI-powered platform to accelerate drug discovery and development for oncology.
Open source
Trialiq20HealthTechOpen source
Fibrotherapeutics20HealthTechDiscover innovative AI therapeutics at fibrotherapeutics.ai, enhancing patient care and advancing health technology.
Open source
- Mhccm17HealthTech
Open source
Aemetis15Climate TechCupertino, United StatesAemetis is a renewable fuels and biochemicals company focused on low-carbon solutions like RNG and SAF.
Open source · Self-hostable
Peptideanswers7AI Drug DiscoveryOpen source
Omniarx7AI-Driven Drug DiscoveryOpen source
Amadeusbio6BiotechAmadeusBio.ai provides an agentic bioinformatics toolkit as a Claude Code plugin for natural language analysis and data retrieval.
Open source
Ultima Genomics68Life SciencesRehovot, Israel$15.0MUnleashing the power of genomics at scale for biological advances and human health.
Open source
Phreesia61HealthTechNew York, United States$120.0MA healthcare software platform automating patient check-in, scheduling, payments, and administrative tasks.
Open source
InsideTracker61HealthTechBoston, United States$45.0MPersonalized health and performance insights based on blood biomarkers and DNA.
Open source
Scala Biodesign56Life SciencesTel Aviv, Israel$21.5MDesigns proteins with superior properties using computational analysis, evolutionary insights, and AI.
Open source
Absci56BiotechVancouver, United States$100.5MAI-powered drug discovery and development platform for biologics.
Open source
Tripo3D56AI-Powered 3D ModelingSan Francisco, United States$50.0MAI-powered platform for generating high-quality 3D models from text or images.
Open source
Enzymit54HealthcareTel Aviv, Israel$10.0MDesigns and creates novel enzymes for sustainable and cost-effective bioproduction.
Open source
- HOHOOTL54Artificial IntelligenceCharlottesville, USA$6.5M
Humans Out of the Loop™ AI solutions
Open source
ProteinQure54BiotechCambridge, United States$15.6MBiotech company using AI and computational platforms to design novel peptide therapeutics.
Open source
Evinature53HealthTechBinyamina, Israel$2.7MEvinature develops evidence-based nutraceutical therapies for gastrointestinal health, focusing on Inflammatory Bowel Disease (IBD).
Open source
Comfy Org53AI Image Generation$30.0MComfy is an AI creation engine for visual professionals, offering granular control over AI models, parameters, and outputs through a node-based workflow on an infinite canvas.
Open source
ZipBio52Life SciencesCambridge, United States$4.0MCompressing biology to develop the next generation of therapies.
Open source
PFx Biotech51BiotechCambridge, United States$5.2MPFx Biotech is developing a novel platform for the discovery and development of protein-based therapeutics.
Open source
Nintex51Automation & RPABellevue, United States$29.0MWorkflow automation and process management software for businesses.
Open source
Cardio Renal49HealthTechParis, France$13.7MFrench digital therapeutics company developing a non-invasive potassium monitoring device for CKD patients.
Open source
Dren Bio48BiotechSan Carlos, United States$156.0MBiopharmaceutical company developing antibody therapeutics for cancer and autoimmune diseases.
Open source
Curoverse48GenomicsBoston, United States$3.2MProvides genomic and biomedical computing solutions for managing and analyzing large datasets.
Open source · Self-hostable
Evogene48Computational BiologyRehovot, Israel$7.9MComputational biology company revolutionizing life sciences product discovery and development using predictive biology.
Open source
Kryon48EnterpriseBellevue, United States$68.0MNintex provides process intelligence and automation solutions to help organizations manage, automate, and optimize business workflows.
Open source
MNDL Bio47Life SciencesSan Francisco, United States$2.0MSynthetic biology startup optimizing gene expression for food and biotech applications.
Open source
Kaelio45HealthTechSan Francisco, United States$500KKaelio is building an AI operating system for healthcare organizations, unifying clinical, operational, and financial data.
Open source
PhenoTA45Life SciencesBoston, United StatesLeveraging AI and novel technology to extract deep health insights from routine blood tests.
Open source
Symbiosis C.M.41HealthcareBoston, United States$10.0MMedical device company addressing anatomical variability in valvular heart disease.
Open source
BoobyBiome41HealthTechLondon, United Kingdom$4.2MDeveloping a microbiome-based diagnostic for early breast cancer detection.
Open source
ShiftCare37HealthTechSydney, AustraliaComprehensive care management platform for home care agencies and IDD providers.
Open source
Khosen Bio35Biotechירושלים, IsraelDeveloping novel therapeutic antibodies for challenging diseases.
Open source
Pharmmies35HealthcareBoston, United StatesPharmmies is a pharmaceutical startup focused on improving pediatric medication delivery through innovative formulations.
Open source
CatAI33HealthcareNew York, United StatesAI-powered remote patient monitoring for home health providers.
Open source
Alvox Bio31Life SciencesCambridge, United StatesAlvox Bio is a life sciences startup developing novel therapeutic antibodies.
Open source
Sauce Technologies30Enterprise SoftwareNew York, United StatesFull-stack technology for mid-market operators, rebuilding architecture to eliminate single points of failure.
Open source
Insight Axis30HealthcareBoston, United StatesOpen source
SensifAI Health29HealthcareTel Aviv, IsraelSensifai desarrolla reconocimiento potenciado por IA, soluciones DeFi seguras y plataformas Web3 innovadoras.
Open source