Mastra is an open-source TypeScript framework for building AI-powered applications and autonomous agents. It provides a comprehensive developer toolkit for prototyping to production-ready deployment, integrating with frontend and backend JavaScript/TypeScript ecosystems like React, Next.js, and Node.js. Mastra enables developers to build, tune, and scale reliable AI agents that can reason, use tools, manage context and memory, and incorporate human-in-the-loop workflows.