Open Source Alternatives to Periodic Labs
60 open source Artificial Intelligence options similar to Periodic Labs, ranked by named competitors first, sector overlap, and our 0-100 AI-readiness score. Each profile notes license and self-hosting where we have it.
Gitar61Artificial IntelligenceSan Francisco, USA$9.0MOpen source
Nous Research63Artificial IntelligenceSan Francisco, United States$70.0MOpen source · Self-hostable
PineAI63Artificial IntelligenceSan Francisco, USA$63.0MOpen source
Viktor62Artificial IntelligenceWarsaw, Poland$64.7MOpen source
Elicit62Artificial IntelligenceOakland, United States$31.0MOpen source
Genesis AI58Artificial IntelligenceSan Francisco, United States$105.0MOpen source
- ESEssential AI58AISan Francisco, United States$239.8M
Open source
xpander.ai57Artificial IntelligenceTel Aviv, Israel$3.0MOpen source
Quotient AI56Artificial IntelligenceBoston, United States$5.5MOpen source
WSO254Artificial IntelligencePalo Alto, USA$63.0MOpen source · Self-hostable
M Magical54Artificial IntelligenceSan Francisco, United StatesOpen source
Neuronics54AI Drug DiscoverySan Francisco, United StatesOpen source
Maneva .54AI Solutions for ManufacturingToronto, CanadaOpen source
- HOHOOTL54Artificial IntelligenceCharlottesville, USA$6.5M
Open source
KiloClaw54Artificial IntelligenceOpen source · Self-hostable
SageOx47Artificial IntelligenceSeattle, USA$15.0MOpen source
Berkshire Grey47RoboticsBedford, USA$275.0MOpen source
Imbue47Artificial IntelligenceSan Francisco, United StatesOpen source
LettaAI31Artificial IntelligenceSan Francisco, United States$1.5MOpen source
PromptQL31Artificial IntelligenceSan Francisco, United StatesOpen source · Self-hostable
pywebagent22Generative AIOpen source
Glama20Agentic AIOpen source
Fiducia AI18Artificial IntelligenceNew York, United StatesOpen source
InstalleraiIT InfrastructureOpen source
New Relic85Enterprise SoftwareSan Francisco, United States$7.2BOpen source
WWT85CybersecuritySt. Louis, USA$63.0MOpen source
Forter85FintechNew York, United States$550.0MOpen source
Ubuntu85Operating SystemsLondon, United Kingdom$63.0MOpen source · Self-hostable
OpenAI84Artificial IntelligenceSan Francisco, United States$493.9BOpen source
DeepL82Artificial IntelligenceCologne, Germany$300.0MOpen source
- GRGrafana Labs80ObservabilityNew York, United States
Open source · Self-hostable
Cursor80Artificial IntelligenceSan Francisco, United States$2.9BOpen source
Cursor (Anysphere)77Artificial IntelligenceSan Francisco, United States$4.8BOpen source
NemoClaw75Artificial IntelligenceOpen source · Self-hostable
Mastra75Agentic AISan Francisco, United States$35.5MOpen source · Self-hostable
MiniMax74Artificial IntelligenceShanghai, China$1.1BOpen source
Google73InternetMountain View, United States$9.1BOpen source
Osaurus71Artificial IntelligenceSan Francisco, USA$63.0MOpen source
Codeium71Artificial IntelligenceMountain View, United States$396.7MOpen source
Airbyte71Data IntegrationSan Francisco, United States$181.0MOpen source · Self-hostable
Arena71Artificial IntelligenceBerkeley, USA$250.0MOpen source
WekaIO70ComputingCampbell, United States$565.0MOpen source
Birdeye70Reputation ManagementPalo Alto, United States$85.0MOpen source
Coframe70AI-Managed PlatformSan Francisco, United States$9.3MOpen source
- ULUltragenyx70BiotechNovato, United States$100.0M
Open source
- MOMongoDB70Big DataNew York, USA$1.5B
Open source
Crunchbase70DataSan Francisco, United StatesOpen source
Pinecone69AI InfrastructureSan Francisco, United States$138.0MOpen source
Sysdig69CybersecuritySan Francisco, USA$608.0MOpen source
Hailo69Edge ComputingTel Aviv, Israel$425.0MOpen source
XBOW69CybersecuritySeattle, United States$215.0MOpen source
LogicGate Risk Cloud68GRCChicago, United States$269.0MOpen source
Starburst67AIBoston, United States$414.0MOpen source · Self-hostable
WuXi AppTec66Drug DiscoveryShanghai, China$40.0MOpen source
Solo.io66Artificial IntelligenceCambridge, USA$174.8MOpen source · Self-hostable
Arize AI65AI ObservabilityBerkeley, United StatesOpen source
Aikido Security65CybersecurityGhent, Belgium$84.4MOpen source
Nx64Software DevelopmentSan Francisco, USA$63.0MOpen source
LlamaIndex64Agentic AIUnited StatesOpen source
Oumi PBC64Artificial IntelligenceSan Francisco, USA$63.0MOpen source
| Company | Sector | License | HQ | Funding | Score |
|---|---|---|---|---|---|
| Artificial Intelligence | Open source | San Francisco, USA | $9.0M | 61 | |
| Artificial Intelligence | Open source · Self-hostable | San Francisco, United States | $70.0M | 63 | |
| Artificial Intelligence | Open source | San Francisco, USA | $63.0M | 63 | |
| Artificial Intelligence | Open source | Warsaw, Poland | $64.7M | 62 | |
| Artificial Intelligence | Open source | Oakland, United States | $31.0M | 62 | |
| Artificial Intelligence | Open source | San Francisco, United States | $105.0M | 58 | |
| ESEssential AI | AI | Open source | San Francisco, United States | $239.8M | 58 |
| Artificial Intelligence | Open source | Tel Aviv, Israel | $3.0M | 57 | |
| Artificial Intelligence | Open source | Boston, United States | $5.5M | 56 | |
| Artificial Intelligence | Open source · Self-hostable | Palo Alto, USA | $63.0M | 54 | |
| Artificial Intelligence | Open source | San Francisco, United States | — | 54 | |
| AI Drug Discovery | Open source | San Francisco, United States | — | 54 | |
| AI Solutions for Manufacturing | Open source | Toronto, Canada | — | 54 | |
| HOHOOTL | Artificial Intelligence | Open source | Charlottesville, USA | $6.5M | 54 |
| Artificial Intelligence | Open source · Self-hostable | — | — | 54 | |
| Artificial Intelligence | Open source | Seattle, USA | $15.0M | 47 | |
| Robotics | Open source | Bedford, USA | $275.0M | 47 | |
| Artificial Intelligence | Open source | San Francisco, United States | — | 47 | |
| Artificial Intelligence | Open source | San Francisco, United States | $1.5M | 31 | |
| Artificial Intelligence | Open source · Self-hostable | San Francisco, United States | — | 31 | |
| Generative AI | Open source | — | — | 22 | |
| Agentic AI | Open source | — | — | 20 | |
| Artificial Intelligence | Open source | New York, United States | — | 18 | |
| IT Infrastructure | Open source | — | — | — | |
| Enterprise Software | Open source | San Francisco, United States | $7.2B | 85 | |
| Cybersecurity | Open source | St. Louis, USA | $63.0M | 85 | |
| Fintech | Open source | New York, United States | $550.0M | 85 | |
| Operating Systems | Open source · Self-hostable | London, United Kingdom | $63.0M | 85 | |
| Artificial Intelligence | Open source | San Francisco, United States | $493.9B | 84 | |
| Artificial Intelligence | Open source | Cologne, Germany | $300.0M | 82 | |
| GRGrafana Labs | Observability | Open source · Self-hostable | New York, United States | — | 80 |
| Artificial Intelligence | Open source | San Francisco, United States | $2.9B | 80 | |
| Artificial Intelligence | Open source | San Francisco, United States | $4.8B | 77 | |
| Artificial Intelligence | Open source · Self-hostable | — | — | 75 | |
| Agentic AI | Open source · Self-hostable | San Francisco, United States | $35.5M | 75 | |
| Artificial Intelligence | Open source | Shanghai, China | $1.1B | 74 | |
| Internet | Open source | Mountain View, United States | $9.1B | 73 | |
| Artificial Intelligence | Open source | San Francisco, USA | $63.0M | 71 | |
| Artificial Intelligence | Open source | Mountain View, United States | $396.7M | 71 | |
| Data Integration | Open source · Self-hostable | San Francisco, United States | $181.0M | 71 | |
| Artificial Intelligence | Open source | Berkeley, USA | $250.0M | 71 | |
| Computing | Open source | Campbell, United States | $565.0M | 70 | |
| Reputation Management | Open source | Palo Alto, United States | $85.0M | 70 | |
| AI-Managed Platform | Open source | San Francisco, United States | $9.3M | 70 | |
| ULUltragenyx | Biotech | Open source | Novato, United States | $100.0M | 70 |
| MOMongoDB | Big Data | Open source | New York, USA | $1.5B | 70 |
| Data | Open source | San Francisco, United States | — | 70 | |
| AI Infrastructure | Open source | San Francisco, United States | $138.0M | 69 | |
| Cybersecurity | Open source | San Francisco, USA | $608.0M | 69 | |
| Edge Computing | Open source | Tel Aviv, Israel | $425.0M | 69 | |
| Cybersecurity | Open source | Seattle, United States | $215.0M | 69 | |
| GRC | Open source | Chicago, United States | $269.0M | 68 | |
| AI | Open source · Self-hostable | Boston, United States | $414.0M | 67 | |
| Drug Discovery | Open source | Shanghai, China | $40.0M | 66 | |
| Artificial Intelligence | Open source · Self-hostable | Cambridge, USA | $174.8M | 66 | |
| AI Observability | Open source | Berkeley, United States | — | 65 | |
| Cybersecurity | Open source | Ghent, Belgium | $84.4M | 65 | |
| Software Development | Open source | San Francisco, USA | $63.0M | 64 | |
| Agentic AI | Open source | United States | — | 64 | |
| Artificial Intelligence | Open source | San Francisco, USA | $63.0M | 64 |