Profluent
Profluent

Profluent

AI-first company designing novel, functional proteins for therapeutics, diagnostics, agriculture, and biomanufacturing.

About

Profluent is an AI-first company that develops deep generative models to design and validate novel, functional proteins. Their platform leverages large-scale frontier AI models trained on billions of biological sequences to create bespoke proteins for various applications, including therapeutics, diagnostics, agriculture, and biomanufacturing. The company aims to make biology programmable, moving beyond natural discovery to intentionally design solutions for human health and the environment.

Key facts

At-a-glance profile data

Website
profluent.bio
Type
VC
Headquarters
Emeryville, USA
Funds raised
$150M
Portfolio companies
1
Stages
Seed
Series B
Series A
Sector focus
AI
Biotechnology
HealthTech
Life Sciences
Artificial Intelligence & Machine Learning

Recent investments

Recent funding rounds Profluent took part in
DateCompanyRoundAmount
5 Aug 2026Skinbits ApiPre-Seed$6M
Comments
(5)
6 positive0 mixed0 negative
Reddit
r/biotechu/DwarvlingApr 29, 2026Positive

“Profluent Announces Strategic Partnership with Lilly to Develop AI-Designed Recombinases for Genetic Medicine. Very interesting application.”

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Reddit
r/businessu/talkingatomsApr 28, 2026Positive

“Profluent, Lilly partner in genetic medicine deal worth up to $2.25 billion.”

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Reddit
r/CerebroDigitalu/TeslaLegacyApr 28, 2026Positive

“Eli Lilly invierte .250 millones en Profluent: la IA que diseña editores de genes que la evolución nunca produjo.”

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Reddit
r/Muslimu/DhowDaddyNov 24, 2025Positive

“Profluent Raises $106M to Scale Frontier AI Models for Programmable Biology.”

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Reddit
r/MuslimVenturesu/DhowCIONov 21, 2025Positive

“Profluent Raises $106M to Scale Frontier AI Models for Programmable Biology. Profluent just raised a $106M round led by Altimeter Capital and Jeff Bezos’ family office, Bezos Expeditions, bringing total funding to about $150M to scale its “…”

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Frequently asked

What companies has Profluent invested in?

Profluent has invested in Skinbits Api.