645 Ventures
Research-driven, founder-focused venture capital firm partnering with relentless founders building iconic technology companies.
About
645 Ventures is an early-stage venture capital firm that partners with exceptional founders to build transformative software companies. The firm utilizes a data-driven approach, leveraging proprietary software to identify and support high-potential startups, primarily investing at the Seed and Series A stages. They focus on companies that solve real problems, possess deep domain expertise, and demonstrate non-consensus thinking.
Key facts
- Website
- 645ventures.com
- Type
- VC
- Headquarters
- New York, United States
- Funds raised
- $548M
- Portfolio companies
- 110
- Stages
- Pre-SeedSeedSeries ASeries B
- Cheque size
- $3M to $50M
- Sector focus
- Enterprise SoftwareSaaSDeveloper ToolsFintechConsumer
Recent investments
| Date | Company | Round | Amount |
|---|---|---|---|
| 30 Jul 2026 | Ellis AI | Seed | $10M |
| 29 Apr 2026 | General Analysis | Seed | $10M |
| 8 Apr 2026 | Pomo | Seed | $5M |
| 31 Mar 2026 | Variance | Series A | $22M |
| 12 Feb 2026 | UPTIQ | Series B | $25M |
| 12 Nov 2025 | Agency | Series A | $20M |
| 29 Sept 2025 | Alex | Undisclosed round | $17M |
| 1 Jul 2024 | Strada | Seed | $3M |
| 24 Oct 2023 | Flox Inc. | Undisclosed round | $17M |
| 14 Sept 2023 | Strada | Seed | $2M |
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Frequently asked
What companies has 645 Ventures invested in?
645 Ventures has invested in Ellis AI, General Analysis, Pomo, Variance, UPTIQ and 105 more.
SEC filings, insider activity, nonprofit links and pay benchmarks for 645 Ventures:

