# Upstream Bio

**Source:** https://www.startuphub.ai/startups/upstream-bio
**Profile type:** Startup

> Clinical-stage biotech developing a monoclonal antibody targeting TSLP for inflammatory diseases.

## About

Upstream Bio is a clinical-stage biotechnology company focused on developing novel therapies for inflammatory diseases. Their lead program is a monoclonal antibody designed to inhibit the TSLP receptor, a key upstream mediator in multiple inflammatory signaling pathways. By targeting TSLP, Upstream Bio aims to address a broad range of immune-mediated conditions.

## Key facts

- **Slug:** upstream-bio
- **Website:** http://www.upstreambio.com
- **Location:** Waltham, United States
- **Founded:** 2021-01-20 00:00:00
- **Employees:** 75
- **Operating status:** Active
- **Total funding:** $400M
- **Sectors / tags:** Life Sciences, Therapeutics, Biotech, Drug Discovery, Clinical Trials, HealthTech, Monoclonal Antibodies, Immunology
- **Social:**
  - LinkedIn: https://www.linkedin.com/company/upstreambio
  - Twitter: https://twitter.com/UpstreamBio

## Frequently asked

### What does Upstream Bio do?

Upstream Bio is a clinical-stage biotechnology company focused on developing novel therapies for inflammatory diseases. Their lead program is a monoclonal antibody designed to inhibit the TSLP receptor, a key upstream mediator in multiple inflammatory signaling pathways. By targeting TSLP, Upstream Bio aims to address a broad range of immune-mediated conditions.

### How much funding has Upstream Bio raised?

Upstream Bio has raised a total of $400M in funding. The most recent round on record is Series B.

### Where is Upstream Bio headquartered?

Upstream Bio is headquartered in Waltham, United States.

### When was Upstream Bio founded?

Upstream Bio was founded in 2021.

### What industry does Upstream Bio operate in?

Upstream Bio operates in Life Sciences, Therapeutics, Biotech, Drug Discovery, Clinical Trials, HealthTech.

### How many employees does Upstream Bio have?

Upstream Bio has approximately 75 people on record.

### What is Upstream Bio's revenue?

StartupHub estimates Upstream Bio's annual revenue at $13.5M (range $7.1M to $20.7M, 64% confidence), based on comparable companies in the sector.

### What is Upstream Bio's valuation?

StartupHub estimates Upstream Bio's effective valuation at $1.7B (range $1.0B to $2.4B, 10% confidence), based on comparable companies in the sector.

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