# 5 Polymarket Bets Paying Up To 10x NOW
_Bet on the Iranian regime's fall by March 31 at 3% odds on Polymarket for a potential 33x return. See other top bets._
**Published:** 2026-03-20
**Source:** https://www.startuphub.ai/ai-news/prediction-markets/2026/5-polymarket-bets-paying-up-to-10x-now
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The biggest potential alpha is screaming from the Middle East: Will the [Iranian regime fall by March 31](https://polymarket.com/event/will-the-iranian-regime-fall-by-march-31/will-the-iranian-regime-fall-by-march-31)? The market is pricing this at just 3%, meaning a YES bet pays out over 33x your stake. This is a high-risk, high-reward play on geopolitical instability, and the Polymarket Iran regime fall prediction is a bet many are watching.

## 2028 US Election Frontrunners Emerge

Looking ahead to the 2028 US Presidential Election, the Democratic nomination market favors Gavin Newsom at 25% (4:1 odds). This mirrors trends seen in similar markets, and for a deeper dive into 2028 election alpha, check out [Polymarket: 2028 Election Alpha & 5x on Oil?](/ai-news/prediction-markets/2026/polymarket-2028-election-alpha-5x-on-oil). The broader [Polymarket 2028 Presidential Election](/ai-news/prediction-markets/2026/3-polymarket-bets-paying-up-to-6-6x-now) markets are heating up, with potential for significant returns.

## Big Bets, Big Liquidity

For those seeking markets with massive liquidity and clearer outcomes, the [2026 FIFA World Cup Winner](https://polymarket.com/event/2026-fifa-world-cup-winner/2026-fifa-world-cup-winner) market has $336M in volume, with Spain currently at 15% odds. Similarly, the [English Premier League Winner](https://polymarket.com/event/english-premier-league-winner-2023-2024/english-premier-league-winner-2023-2024) is seeing huge action, with Arsenal at 91% odds. These markets reflect strong consensus but offer lower upside compared to the geopolitical plays.

Trading involves substantial risk of loss.

          Polymarket
          

Will The Iranian Regime Fall By March 31/Will The Iranian Regime Fall By March 31

          [View on Polymarket →](https://polymarket.com/event/will-the-iranian-regime-fall-by-march-31/will-the-iranian-regime-fall-by-march-31)
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Original analysis from [startuphub.ai](https://www.startuphub.ai), the #1 AI startup directory.